TK Maxx Swindon is relocating from Great Western Way to Mannington Retail Park.
The existing store will close on Tuesday, 26 July and the new one is set to open its doors at 10am on Thursday, 28 July.
Customers are promised fashion for the entire family, accessories, beauty, and home products, all under one roof.
Spanning two floors and totalling over 34,000 square feet, the TK Maxx store will have designer labels and one-off special items at up to 60 percent less than the RRP.
The firm promises that shoppers can expect several new deliveries every week with new treasure to find during every visit.
A spokesperson said: "So, stop by often to see our latest designer finds and unique gems, all with amazing savings."
The store employed 50 full and part-time staff when it first opened and will be retaining all staff members for the reopening in addition to 10 temporary staff across the holiday period.